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- (1)
- (176)
- (9)
- (17)
- (39)
- (70)
- (52)
- (9)
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- (120)
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- (494)
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Filtered Search Results
Medchemexpress LLC Suberoyl bis-hydroxamic acid | 38937-66-5 | 95.0% | 204.22 | 100 MG
Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Suberoyl bis-hydroxamic acid (SBHA) is a competitive and cell-permeable inhibitor targeting HDAC1 and HDAC3, demonstrating ID50 values of 0.25 μM and 0.30 μM, respectively. This compound sensitizes multiple myeloma (MM) cells to apoptosis and activates mitochondrial apoptotic pathways. It is also used in the study of medullary thyroid carcinoma (MTC).
- Inhibits HDAC1 and HDAC3.
- Enhances apoptosis in multiple myeloma cells.
- Facilitates mitochondrial apoptotic pathways.
- Applicable for medullary thyroid carcinoma research.
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Medchemexpress LLC Farudodstat | 1035688-66-4 | 99.7% | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Farudodstat is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for the human DHODH enzyme. It inhibits protein synthesis by activating AP-1 transcription factors, induces apoptosis, and significantly prolongs survival in acute myeloid leukemia (AML) xenograft mice.
- Potent Dihydroorotate Dehydrogenase (DHODH) inhibitor
- IC50 of 35 nM for human DHODH enzyme
- Inhibits protein synthesis via activation of AP-1 transcription factors
- Induces apoptosis
- Substantially prolongs survival in acute myeloid leukemia (AML) xenograft mice
- Inhibits leukemic cell proliferation
- Increases cleaved caspase 8
- Decreases viability and induces differentiation in primary acute myeloid leukemia blasts and myelodysplastic syndrome samples
- Causes downregulation of EIF4B and RPL6 proteins
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eMolecules 126291-66-5 | METHYL 1-ACETYLPIPERIDINE-4-CARBOXYLATE | AstaTech | MFCD02862113 | 185.223 | C9H15NO3 | 95.000 | COC(=O)C1CCN(CC1)C(C)=O | 0.25g | 437210176
METHYL 1-ACETYLPIPERIDINE-4-CARBOXYLATE | AstaTech | 126291-66-5 | MFCD02862113 | 185.223 | C9H15NO3 | 95.000 | COC(=O)C1CCN(CC1)C(C)=O | 0.25g | 437210176
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Aobchem AOBCHEM
5000952276 4-FORMYL-3-METHOXYPHENYLBORONI
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Aobchem AOBCHEM
5000952324 3-FORMYL-4-HYDROXYPHENYLBORONI
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Aobchem AOBCHEM
5000953140 3-FORMYL-2-METHOXYPHENYLBORONI
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Aobchem AOBCHEM
5000966719 ETHYL 4-FORMYL-2 5-DIMETHYLBEN
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Aobchem AOBCHEM
5000975253 3-FORMYL-5-TRIFLUOROMETHYLBENZ
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Aobchem AOBCHEM
5000975394 3-FORMYL-5-TRIFLUOROMETHYLBENZ
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Aobchem AOBCHEM
5000976425 4-FORMYL-1-NAPHTHALENECARBONIT
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Aobchem AOBCHEM
5000979578 2-FORMYL-4-METHYLPHENYLBORONIC
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Aobchem AOBCHEM
5001011581 3-FORMYL-5-ISOPROPOXYPHENYLBOR
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Aobchem AOBCHEM
5001013342 3-FORMYL-5-METHYLBENZONITRILE
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Aobchem AOBCHEM
5001022344 2-BROMO-4-FORMYL-5-METHOXYPHE
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Aobchem AOBCHEM
5001022345 2-BROMO-4-FORMYL-5-METHOXYPHE
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